A new study was published August 14th in the American Journal of Gastroenterology:
* Mather JF, et al “Impact of famotidine use on clinical outcomes of hospitalized COVID-19 patients” Am J Gastroenterol; August 14, 2020.
The study concluded that “Famotidine use was significantly associated with a reduction in death and either death or intubation.” Famotidine users were 63% less likely to die in hospital, and 53% less likely to experience either death or intubation.
The death or intubation end-point is a lower percent because the patient would be in that category if either or both things happened to them, intubation or death. And since not every patient who is intubated also dies, you have more patients who experience one or the other or both, than the number who simply die.
This was a single-center retrospective observational study at Hartford Hospital, a tertiary care facility.
What is disturbing about this study is that only 9.5% of patients were given famotidine, despite a previous study showing that it reduces risk of death. This resulted in the overall death rate at the hospital of 21.8%. Since we know the death rate of those who used famotidine was 63% lower than those who did not, we can calculate the death rate without the famotidine patients. There were 878 patients in the study. And 14.5% died in the famotidine group, as compared to 26.0% in the non-famotidine group.
The death rate of 26% is terrible. Hospitals using MATH+ protocol have death rates of 6.6% or 3.3% using two examples. If the hospital used MATH+ Protocol, which includes famotidine, the death rate could have been 6.6% instead of 26.0%, resulting in 194 fewer patients dying for every 1000 treated.
Suppose the Hospital merely used famotidine in every patient, rather than the entire MATH+ Protocol. At 14.5% death rate instead of 26%, 115 patients out of every 1,000 would live instead of dying. This hospital and many others are needlessly killing patients by not applying knowledge from published studies on what does and does not work in Covid-19 patients.
The Hartford Hospital is still using hydroxychloroquine in late-stage patients, and/or azithromycin, despite the poor performance in recent studies of azithromycin or hydroxychloroquine with azithromycin. Ivermectin and doxycycline, combined, has a much better outcome in studies.
Patients are needlessly dying because hospitals don’t apply knowledge from recent studies to patients, and health authorities don’t intervene to require use of best known practices.
Ronald L. Conte Jr.
Note: The author of this article is not a doctor, nurse, or healthcare provider, and this article does not offer medical advice — or does it?
Disclaimer: This Website Does Not Offer Medical Advice.
However, I am so sick of sitting here watching vast numbers of persons get sick and die from Covid-19 needlessly. There is enough evidence from legitimate studies to reduce the infection rate, the rate of hospitalization, the percent of hospitalized patients needing ICU care or mechanical ventilation, and especially to reduce the death rate from Covid-19. There are NINETEEN studies showing having vitamin D blood levels merely in the normal range does exactly that, reduce infection rate, death rate, and the other outcomes as well.
Then there is ample evidence that taking famotidine reduce death rate and need for intubation. A recent study published in the American Journal of Gastroenterology — there is no more prestigious journal for this subject that the AJG — showed that use of famotidine, and over-the-counter medication, reduced the death rate from 26% to 14.5%. For every 100,000 Covid-19 patients who are hospitalized (i.e. the sickest Covid-19 patients) famotidine saves 11,500 lives. A freaking OTC antacid medication does that. So why aren’t medical authorities recommending this?
The Front Line Covid-19 Critical Care Alliance, a working group of 10 physicians with absolute top line credentials who have worked with many Covid-19 patients has been recommending famotidine and a number of other medications that studies show work. One hospital using this Protocol, called MATH+, has a death rate of only 6.6%; another, 3.3%; whereas the typical Covid-19 hospital death rate is 24 to 27%. People are dying needlessly.
Here’s my medical advice: Take vitamin D (10,000 IU/day). Take famotidine (20 to 40 mg/day). Don’t die needlessly from Covid-19.