This article discusses a multi-center placebo-controlled randomized clinical trial on the use of Honey and Black cumin seeds (Nigella sativa) as a adjunct treatment for Covid-19. Note well that this is not suggested as the sole treatment for Covid-19, but as something to take along with the standard of care (usual treatment).

Sources of information:
* Study: Honey and Nigella sativa against COVID-19 [PDF of full study]
* Video on study: Dr. Mobeen Syed
* Study on Nigella sativa: Another study discusses the components of Nigella sativa and possible benefits against Covid-19

Study Method: “Patients were randomly assigned in 1:1 ratio to receive either [the intervention] honey (1 gm/Kg/day) and Nigella sativa seeds (80 mg/Kg/day) or placebo up-to 13 days along with standard care. The outcomes included symptom alleviation, viral clearance, and a 30-day mortality in intention-to-treat population. This trial was registered with, NCT04347382”

The patients were further divided into moderate cases, receiving the intervention or the placebo, and severe cases, with intervention or placebo. All patients received standard of care. So HNS (honey and Nigella sativa seeds) was not the only treatment. There were no adverse effects in patients taking HNS. All results were statistically significant, and HNS showed clear benefits in all endpoints:
1. Days to alleviate symptoms were fewer in patients taking HNS
2. Days to viral clearance were fewer in HNS
3. Clinical score on Day 6 was better in HNS
4. Hospital discharge by Day 6 was much higher in HNS severe patient group
5. 30-day mortality was 4% in HNS group and 18.87% in control group for severe patients

In the moderate group, no patients died with HNS and one patient died with the placebo (plus standard care). The results for mortality were statistically significant, and for the other end points results were highly statistically significant.

The use of Honey with Nigella sativa seeds (HNS) along with standard care for Covid-19 patients showed clear benefits in this study, with no adverse effects.

HNS is recommended as part of the I-MASK Protocol. The FLCCC Alliance says: “We are a group of expert clinicians who are driven only by our desire to save lives. We continually update our protocols based on clinical observations as well as the best studies of modes of prevention and treatment therapies for COVID-19.” Their website is recommended reading: Covid-19 Protocols.

Note: Be aware that infants younger than 12 months should not consume honey of any kind due to the risk of infant botulism. Also, none of the interventions or treatments discussed in articles at are appropriate for infants or young children, unless approved by your pediatrician.

Ronald L. Conte Jr.
an author, not a doctor